Selank 20 mg

What is the Selank peptide?

Selank is a synthetic heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP), designed as a stable analogue of a fragment of the natural tetrapeptide tuftsin, extended with a characteristic Pro-Gly-Pro motif at the C-end. It was developed at Russian neuroscience and immunochemistry research centers as a model compound for studying the regulation of neuropsychiatric processes and the interaction of the nervous system with the immune system.

In experimental studies, Selank has been used to analyze mechanisms modulating emotional information processing, stress response and neurochemical balance in the central nervous system. Its effects on the expression of selected neurotrophic factors, the activity of signaling pathways related to the GABA-ergic system and the regulation of the expression of genes involved in neuronal adaptation were described. In in vitro and in vivo models, attention was paid to its potential ability to stabilize neuronal function under conditions of environmental stress and oxidative stress.

Due to its precisely defined chemical structure, good stability and reproducibility of the observed effects in experimental models, Selank is used in neurochemistry, molecular biology and neuro-immune axis regulation studies. It is also sometimes described in the scientific literature as a peptide that modulates the activity of neurotransmitter systems, making it a useful tool in experimental analyses of cognitive and emotional functions.

Technical parameters of Selank peptide:

Name of substance: Selank
Type of relationship: Synthetic peptide - heptapeptide analogue of tuftsin, extended by the terminal motif Pro-Gly-Pro
Amino acid sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP).
Summary formula: C₃₃H₅₇N₁₁O₉.
Molecular weight: ~751.9 g/mol
CAS number: 129954-34-3
Physical form: White or almost white powder after freeze-drying
Solubility: Well soluble in aqueous solutions

Product quality (Selank 20 mg)

Our Selank peptide product has been tested by a certified Polish laboratory. You can see the results in the product gallery.

What does the product package (Selank 20 mg) contain?

The ordered product will come packaged in a sturdy tube resistant to transport damage, and inside it you will find:

• Powder vial: (Mannitol + Selank acetate 20 mg + 5 mg GHK-Cu)
• Vial of saline 10 ml
• Atomizer (for spraying a portion of the solution onto a laboratory slide)
• Funnel (helps pour solvent into the peptide vial)

It is worth noting that the lyophilized powder will be white and blue in color due to the presence of the GHK-Cu peptide. The volume of powder in the vial may seem small, but this does not affect the peptide content measured in milligrams.

The safety data sheet (SDS) for this product can be downloaded here

How to prepare the solution for the laboratory test?

• unscrew the stoppers from both vials
• Transfer the liquid from the liquid vial to the powder vial
• cap the vial with the powder with the original stopper
• Mix carefully (no sudden movements)
• unscrew the cap and screw on the atomizer

The vial contains 70 puffs of 285 mcg Selanc.

Storage and transportation

In dry form, the peptide should be stored at room temperature away from direct sunlight. Even longer transportation by courier will not affect the stability and quality of the product.

In wet form (after preparing the solution), the peptide should be in the refrigerator all the time and used up within 40 days.

Research use of the product (Selank 20 mg)

The product is intended exclusively for in vitro research work and serves as a specialized reagent used in molecular and cellular analyses of nervous system function. In a laboratory environment, it is used in, among other things:

• studying the interaction of short peptides with selected cellular structures, receptors and markers involved in neuronal and neurochemical signaling,

• To evaluate the effects on the expression of regulatory and neurotrophic factors in controlled cell cultures,

• Analysis of changes in protein profiles and activity of potential signaling pathways specific to cells with a neuronal and neuroglial phenotype,

• Supporting validation procedures, benchmarking and optimization tests in molecular biology, biochemistry and neurochemistry research.

• observation of droplets, sediments, and crystalline structures using optical and polarization microscopy.
• analyses of the size and distribution of droplets produced by the atomizer, including by depositing them on a microscope slide;
• evaluation of the size and distribution of aggregates present in the solution by dynamic light scattering (DLS);
• performing UV-Vis spectrophotometric analyses,

Disclaimer

The product is not a drug, food product or dietary supplement. The product is classified as a chemical reagent/reference material authorized in the European Union under the European REACH Act, and can only be used for laboratory scientific research. Educational materials about Selank substance posted on our site are written on the basis of scientific research on the substance. These studies were performed by qualified scientific centers around the world and are not product specific.