Ipamorelin 40 mg

What is Ipamorelin?

Ipamorelin is a synthetic pentapeptide with the sequence Aib–His–D-2-Nal–D-Phe–Lys–NH₂. It represents a selective growth hormone secretagogue analogue containing atypical amino acid residues (Aib and D-amino acids) that increase metabolic stability. This compound was developed as part of research on GHS-R1a receptor ligands (the ghrelin receptor). Due to its precisely defined structure and good solubility in aqueous environments, Ipamorelin has become a useful model for studying GHS receptor-dependent peptide signaling.

In experimental studies, Ipamorelin has been used to analyze mechanisms related to the activation of the GHS-R1a receptor, the modulation of G protein-dependent signaling pathways, and cellular responses in in vitro and in vivo models. Its effect on the expression of selected genes regulated by ghrelin pathways and on signaling processes in experimental systems has been described. Attention has been drawn to its selective interactions with G protein-coupled receptors and its indirect effect on signaling homeostasis under preclinical conditions.

Due to its unambiguously defined chemical structure and high reproducibility of observed biological effects in experimental models, Ipamorelin is used as a research tool in molecular biology, experimental endocrinology, and experimental pharmacology. In the scientific literature, it is also utilized as a reference ligand for the GHS-R1a receptor to assess signaling processes and to validate analytical methods used in the study of short bioactive peptides. The preparation is intended exclusively for research work.

Technical parameters of the Ipamorelin peptide:

• Substance name: Ipamorelin
• Type of compound: synthetic peptide — a pentapeptide analog of growth hormone secretagogues
• Amino acid sequence: Aib–His–D-2-Nal–D-Phe–Lys–NH₂
• Formula: C₃₈H₄₉N₉O₅
• Molecular weight: ~711.9 g/mol
• CAS Number: 170851-70-4
• Physical form: white to off-white lyophilized powder
• Solubility: soluble in aqueous solutions

Product quality (Ipamorelin 40 mg)

Our product has been tested by a certified Polish laboratory. The results are available in the product gallery.

What does the product packaging contain (Ipamorelin 40 mg)?

The ordered product will come packaged in a sturdy tube resistant to transport damage, and inside it you will find:

• Vial with powder (Mannitol + Ipamorelin 40 mg + 5 mg GHK-Cu)
• Vial of saline (3%DMSO) 10 ml
• Atomizer (for spraying a portion of the solution onto a laboratory slide)
• Funnel (helps pour solvent into the peptide vial)

How to prepare the solution for the laboratory test?

• unscrew the stoppers from both vials
• Transfer the liquid from the liquid vial to the powder vial
• cap the vial with the powder with the original stopper
• Mix carefully (no sudden movements)
• unscrew the cap, remove the ring from the seal (important to keep it tight) and screw on the atomizer

We obtained 10 ml of solution, which is enough for about 70 atomizer presses of 0.57 mg of Ipamorelin.

Storage and transportation

In dry form, the peptide can be stored at room temperature away from direct sunlight

In wet form (after the solution is prepared), the peptide should be refrigerated for up to 40 days at all times.

Research application of the product (Ipamorelin 40 mg)

The product is intended for research use only under conditions in vitro, where it can serve as a specialized reagent for molecular, biochemical, and cellular analyses regarding the activity and interactions of peptides with receptor systems related to ghrelin signaling. In laboratory models, it is used for:

• studies on the interactions of Ipamorelin with the GHS-R1a receptor and selected elements of receptor systems;
• assessment of receptor activity and changes in intracellular signaling pathways in relevant cell models;
• analyses of changes in the expression of selected genes, proteins, and biological markers in cell cultures;
• conducting comparative research on the activity of Ipamorelin and other GHS-R1a receptor peptide ligands;
• support for validation and comparative methods within molecular, biochemical, and cellular analyses;
• observation of droplets, sediments, and crystal structures using optical and polarizing microscopy;
• analyses of the size and distribution of droplets produced by the atomizer, including by depositing them on a microscope slide;
• evaluation of the size and distribution of aggregates present in the solution by dynamic light scattering (DLS);
• conducting spectrophotometric analyses using the UV-Vis method, within a range appropriate for the properties of the tested peptide and the analytical method used.

Disclaimer

The product is not a drug, food product or dietary supplement. The product is classified as a chemical reagent/reference material approved for marketing in the European Union, and can only be used for laboratory scientific research. The educational materials on our website are written on the basis of scientific research on the substance and do not apply to a specific product. The safety data sheet (SDS) for this product can be downloaded